The Lamborghini Murciélago Roadster, introduced in 2004 as the convertible variant of the Murciélago coupe, was produced until 2010. Approximately 4,099 Murciélago units were made in total across all variants, with the Roadster comprising a smaller, rarer portion of this figure. It succeeded the Diablo as Lamborghini's flagship V12 model, embodying the brand's bold design and performance ethos during the early 2000s under Audi's ownership.

Powered by a 6.2-liter V12 engine in early models, later upgraded to a 6.5-liter V12 in the LP 640 variant, the Roadster delivered between 572 and 631 horsepower, depending on the version. It achieved a 0-60 mph time of around 3.5 seconds and a top speed exceeding 200 mph (with the roof on). A unique feature is its manually detachable fabric roof, designed for low-speed use, prioritizing style over practicality. For collectors, the Murciélago Roadster holds value due to its limited production, iconic scissor doors, and status as one of the last analog-era Lamborghinis before modern hybridization. Special editions like the LP 650-4 Roadster, with only 50 units made, are particularly sought after, with values appreciating in recent years on the classic car market.